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EventsDIABETES MESSE Bio International Convention BioNano 2010 SEPAWA CAN - Newsletter
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CAN-LifeCAN GmbH is developing various standardized in vitro toxicity assays for nanoparticles. A key feature is the systematic variation of nanoparticle size, shape and surface properties and determination of the respective influence on interactions with human tissue models. CAN GmbH has therefore established test facilities with a variety of cell lines from the skin, respiratory system and bowel. The experimental setup also includes advanced confocal microscopy techniques as well as automated screening and electron microscopy imaging. This research area also includes the generation of a database to allow the correlation of biological features (e. g. toxicity and cellular uptake) with physico-chemical particle properties. Ultimately, the combination of broad synthetic expertise and the generated biological data will lead to a straightforward development, such as innovative nanoparticle-based biomedical markers for molecular targeting. |
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